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Total-Zymes® Plus - For Larger Pets 100 tablets

Availability: In stock

Regular Price: $50.99

Special Price $49.99

Quick Overview

Total-Zymes® Plus For Larger Pets!
Pet Digestive Aid      New! 14 Probiotics Plus 16 Enzymes
Pet Digestive Aid      Healthy digestive system
Pet Digestive Aid      Healthy immune system
Pet Digestive Aid      Reduced food intolerance
Pet Digestive Aid      Smaller and firmer stools

  Product Description    More Information    Ingredients    Directions    Supplement Facts Box    FAQ  


New Larger size tabs for bigger pets!

 All the benefits of 16 Enzymes and 14 Probiotics in a delicious and convenient, treat-form tablet!

Pet Digestive Aid      1 tablet treats one cup of pet food

Pet Digestive Aid      Total-Zymes® PLUS is a full strength combination of 16 vegetarian digestive and systemic enzymes

Pet Digestive Aid      With 14 Probiotics plus Pre-Biotics in a tasty chewable tablet

Pet Digestive Aid      Total-Zymes® PLUS for larger pets, will help combat digestive problems, while enhancing a beneficial bacterial balance

Pet Digestive Aid      Supports pets with allergies, itching and painful stiff joints

Pet Digestive Aid      Improve digestion, control yeast overgrowth 

The Best Probiotics Plus Digestive Enzyme Pet Supplement Product On The Market Just Got Better!

Now with the only patented stabilized glutamine in the world- MGG chelate. This is why it works better and faster then the rest.

Our pets digestive system is the first line of defense for the immune system; keeping it in optimal condition benefits overall health and immunity.

Total-Zymes® PLUS is recommended for issues such as loose stool, maintaining healthy skin and coat, sensitive stomach, hairballs, low energy, and even bad breath. Total-Zymes® PLUS will help your pet achieve total digestive health by improving digestion and absorption of your pet's diet, no matter what you feed them.

Total-Zymes® PLUS is formulated with 16 vegetarian enzymes and 14 species of live stable ProBiotics plus Pre-Biotics. Each tablet supplies one Billion CFUs of those 14 different species of live ProBiotics.

Nearly every pet can benefit from supplementation with enzymes and probiotics. Even healthy pets may improve their absorption and utilization of nutrients through the use of enzymes and probiotics.

Pets have billions of bacteria living in their gut. Some are harmful (pathogenic), but many are beneficial. Keeping a balance between the good and the bad bacterial is critical to maintaining good health.

Probiotics help keep bad bacteria and yeast from growing in the intestinal tract, and confer many other proven benefits, including vitamin production and keeping the immune system healthy in pets.

Probiotic bacteria in our pets bodies are essential to maintaining good health, as proven by many years of scientific research! Normally there are an abundance of friendly bacteria, but certain circumstances can lead to a depletion of these essential microorganisms.

Total-Zymes® PLUS uses Lactobacillus Acidophilus DDS-1 originally discovered and researched by Dr. Khem Shahani. Lactobacillus Acidophilus DDS-1 is the most researched probiotic in the world. Total-Zymes® PLUS also is formulated with 13 other live, viable probiotics from Nebraska Cultures using a patented stabilization method and then blended into our pet formula.

There is no other product on the market like it. 

Total-Zymes® PLUS is a superior product and the most complete to help all pets live a healthy and  longer life.

Also consider Total-Zymes® Plus Pack. Save 25% Pack of 4 for the price of three, Four 100 ct bottles

Pet Digestive Aid      Eight Signs you Pet Needs Probiotics and Enzymes

 Pet Digestive Aid      Can enzymes support my pets pancreas?  

Pet Digestive Aid       Why does my pet need enzymes and probiotics?

Download: Nutrition Label
Comparison: To other combination products
Read: What Are Probiotics?
Read: What Are Digestive Enzymes?

probiotics for dogs




Total-Zymes® PLUS  with            LEADSVegerarian Approved 
The L.E.A.D.S.® system (Live Enzyme Activated Delivery System®) optimizes our pro-biotics' effectiveness in your pet's digestive tract helping the pro-biotics implant and colonize. Live Enzyme Activated Delivery System ® (L.E.A.D.S. ®) insures assimilation at a cellular level. This particular combination of mineral cofactors helps to activate each individual enzyme for maximum particle digestion and complete nutrient distribution throughout the body. It increases the formula's bioavailability.

Using Total-Zymes® PLUS on your pet's food is as close as you can get to the benefits of an all raw food diet.

All Natural Ingredients, the facility that manufactures NWC Naturals® pet products is Certified and is in full compliance with GMP Requirements for Dietary Supplements.  They also utilize a third party testing lab, that insures that all our quality ingredients are tested and retested for purity and quality.Human Grade.

Also utilize a third party testing lab that insures that all the quality ingredients are tested and retested for purity and quality. All NWC Naturals® products are Made and bottled in a USA facility.

 The probiotics in Total-Zymes®  Plus;


pet enzymes14 stabilized strains of live probiotics from Nebraska Cultures!


pet enzymesHelp manufacture B vitamins, controls constipation and diarrhea   


pet enzymesImprove digestion, control yeast overgrowth 


pet enzymesRemove toxins from the body


pet enzymes Human grade ingredients but formulated just for pets


Total-Zymes®  Plus For Pets does NOT contain any animal based enzymes and here is why:


Supplemental pancreatic, plant, and microbial enzymes are all designed to enhance digestion. However, plant and microbial enzymes use a "pro-active" approach and begin working on foods soon after ingestion. Pancreatic enzymes do not go to work right away. Pancreatic enzymes usually begin working approximately 30 minutes after food reaches the stomach and up to 80% of the enzymes are destroyed in the stomach.


Pancreatic Enzymes or Non-animal Enzymes>>Read More


Every pet can benefit from supplementation with enzymes and probiotics.


Even healthy pets may improve their absorption and utilization of nutrients through the use of digestive enzymes and probiotics. By using a supplemental enzyme on your pet’s food you free up their body's digestive system. When enzymes are missing from our pet's food, the full burden of digestion falls on the pet's own digestive system.


How to handle and store Total-Zymes® PLUS


All pro-biotics will benefit from proper storage to insure a long shelf life with full potency. Nothing in Total-Zymes® PLUS actually goes stale or bad with time. The potency will go down depending on how it is stored. If stored at room temperature we guarantee full potency through the date printed on the jar.


Since we only use fully stabilized versions of the pro-biotics and we formulate with double what we claim on the label, we can guarantee the potency that is listed on the label if left out at room temperature. When Total-Zymes® PLUS is stored in the refrigerator you can add 6 months to the life of the product.


When you store Total-Zymes® PLUS in the freezer you can add one full year to the life of the product. Always keep the lid tightly closed. When you receive your product check the date and decide if you will be using the product up by that date. If not, then either refrigerate or freeze the product accordingly.

The List of 16 Enzymes in our new Combination Tablet,

pet enzymes Protease 6.0; Is used to break down proteins to peptides. It will not digest protein to amino acids. A second enzyme is necessary for that to happen.


pet enzymes Protease 3.0; Is used to break down proteins in a different PH range.


pet enzymes Protease 4.5; Is used to break down proteins in a different PH range then the other two.


pet enzymes Peptidase; Help digest protein molecules. Four varieties of protease enzymes have been combined in this formula to compensate for higher protein diets of pets.


pet enzymes Amylase;  An enzyme that breaks down sugars and starches. Good for those hidden sugars in pet treats. And helps digest corn, potatoes, rice ect.


pet enzymes Alpha-Galactosidase; This enzyme breaks down carbohydrates, such as vegetables, whole grains. It can help prevent the gas and other gastrointestinal symptoms.


pet enzymes Beta-Glucanase; This enzyme is used to breakdown carbohydrates, specifically starches.


pet enzymes Diastase; Sometimes called maltase is an enzyme that is the catalyst in the hydrolysis of disaccharide maltose to the simple sugar form - glucose.


pet enzymes Lipase; Will digest lipids or fats as they are commonly called. Lipase  is critical to digest that fat in the diet that supports a healthy coat and skin.


pet enzymes Cellulase; Works on Cellulose, an indigestible fiber found in many fruits and vegetables.


pet enzymesPectinase; Breaks down fruit and vegetable pectins and aids in detoxifying and lifting heavy metals in pets. A much needed enzyme for your pet. Your pet gets heavy metal build up just like we do,  this enzyme helps rid  your pet of these toxic metals.


pet enzymesPhytase;  Breaks down carbohydrates, specifically phytates in plants. It can increase mineral absorption and the bio-availability of iron, zinc, calcium, and magnesium. A needed enzyme to help digest pet food with potatoes or carrots ect. Some companies say you do not need this very important enzyme it was put into the formula because pet foods do have carbohydrates and this enzyme helps properly digest them.


pet enzymes Hemicellulase; Is used to breakdown carbohydrates, especially polysaccharides such as hemicelluloses, which are found in plant foods.


pet enzymes Bromelain; Is most notable for its effectiveness in normalizing inflammation and decreasing swelling. As a natural systemic enzyme with many uses.


pet enzymes NEW! LactaseHelping digest, Lactose and milk sugars. Lactase is required to break down lactose (a primary sugar found in mammalian milk).  Also to help digest yogurt, milk products and cheese.


pet enzymes NEW! Glucoamylase;  Is used to breakdown carbohydrates, specifically polysaccharides, simple sugars. Many new dog treats have hidden sugar.


Probiotic Ingredients:

pet enzymesAcidophilus DDS-1 strain- researched and developed by Dr. Khem Shahani for over 77 years, Acidophilus is the most effective pro-biotic strain, defending against the greatest number of pathogens; inhibiting 11 disease-causing bacteria. Called the "sticker strain," Acidophilus has the ability to actually cling to the intestinal wall without harming it. In fact, it is best known for its ability to move un-disrupted through the stomach and into the intestines where it eats away at disease causing bacteria. It is known for reducing the occurrence of constipation and diarrhea, increasing nutrient uptake (especially calcium), preventing food poisoning and alleviating dermatitis and other skin and coat conditions.

pet enzymesB. bifidum- Is a normal inhabitant of the intestines. Found in large numbers, the numbers of bifidobacteria decrease with age. B. bifidum helps detoxify the intestines and promote regular bowel movements.


pet enzymesBacillus coagulans-  Bacillus coagulans has been added by the EFSA to their Qualified Presumption of Safety (QPS) list] and has been approved for veterinary purposes by the U.S. Food and Drug Administration's Center for Veterinary Medicine, as well as by the European Union and is listed by AAFCO for use as a direct fed microbial in livestock production. It is often used in veterinary applications, especially as a probiotic in pigs, cattle, poultry, dog and cats.


pet enzymesBifidobacterium breveDifferent species and/or strains of bifidobacteria may exert a range of beneficial health effects, including the regulation of intestinal microbial homeostasis, the inhibition of pathogens and harmful bacteria that can colonize and infect the gut mucosa Bifidobacterium breve is helping to modulate the local and systemic immune responses.


pet enzymesB. lactis (B. animalis )-  B. lactis is a Gram-positive anaerobic rod-shaped bacterium, which can be found in the large intestines of most mammals, including humans. Bifidobacterium animalis and Bifidobacterium lactis were previously described as two distinct species. Presently, both are considered B. animalis with the subspecies Bifidobacterium animalis subspecies animalis and Bifidobacterium animalis subspecies lactis. Both names B. animalis and B. lactis are still used on product labels, as this species is frequently used as a probiotic in pet products.


pet enzymesB. longum -  Aids in the cleansing and health of the colon and liver.


pet enzymesL. brevis-  Lactobacillus brevis is a species of lactic acid bacteria, all of which are Gram-positive, non spore forming organisms whose main metabolic pathway involves fermenting hexose sugars to produce lactic acid. L. brevis can be isolated from the food sources in inhabits, one example being kimchi. This bacteria is probiotic, and improves the immune system.


pet enzymesL. casei-  Is reported to be one of the most potent defenders from Listeria bacteria. It is also known for its ability to induce an immune response that is helpful in supporting a healthy urinary tract


pet enzymesL. plantarum-  Can be found in naturally fermented foods. It is found in the large intestine where it helps to break down protein into usable nutrients, thus normalizing inflammation.L. plantarum is also known for repairing free radical damage from aging, stress, antibiotics, chlorinated water and other chemicals. It also contains an antioxidant that helps protect against the toxins present in the Standard Pet Diet and in treating the pain caused by arthritis.


pet enzymesL. rhamnosus-  Is one of the more highly studied probiotic strains, primarily used in support of normal gastrointestinal health. It also aids the body in balancing the normal flora ecology and supports a healthy urinary tract.


pet enzymesLactococcus lactis- Has been shown through research to produce a high amount of lactic acid, which is able to inhibit the growth of H. pylori, thusly reducing the associated inflammation and risk of peptic ulcers. Is also beneficial to supplement the diet in maintaining normal intestinal flora.


pet enzymesL. salivarius- Has been shown through research to produce a high amount of lactic acid, which can inhibit the growth of H. pylori bacteria.


pet enzymesStreptococcus thermophilus- Is known for repairing free radical damage from aging, stress, antibiotics, chlorinated water and other chemicals. It also contains an antioxidant that helps normalize inflammation and protect against the toxins.


pet enzymesL. Bulgaricus- Lactobacillus bulgaricus is one of several bacteria used for the production of yogurt. It is also found in other naturally fermented products.


The other ingredients in Total-Zymes® Plus


pet enzymesPre-biotics- Inulin IQ FOS (Fructooligosaccharides)- one of the best-known pre-biotics, is a class of simple carbohydrates found naturally in certain plants, such as Jerusalem artichokes, onions, and bananas. FOS is known to promote the growth of beneficial bacteria in the gastrointestinal tract. It has been shown to stimulate growth of bifidobacteria in the colon where many diseases first take root. Supplementing with FOS can greatly increase metabolic activity in the colon and help relieve constipation and reduce the production of intestinal putrefactive substances. Healthy colon function is vital to a properly functioning immune system


pet enzymesThe only patented stabilized glutamine in the world- MGG chelate- This stabilized Glutamine re-writes the book on utilizing anabolic nitrogen molecules to help cleanse and fortify the body. Glutamine yields beneficial effects on the intestinal mucosa and is also the major metabolic fuel for the small intestine. The addition of the chelated glutamine to Total-Zymes® Plus Tablets greatly improves the stability and colonization characteristics of beneficial bacteria in the pet's intestinal tract and is an essential nutrient that is required by the intestinal cells. It can actually help repair a damaged intestinal tract.



Live Enzyme Activated Delivery System® (L.E.A.D.S.®)- Like all of NWC Naturals® Pet Products LLC Total-Biotics® contains our exclusive Live Enzyme Activated Delivery System®. It is this delivery system that guarantees assimilation and utilization of the nutrients at the cellular level. L.E.A.D.S.® (Live Enzyme Activated Delivery System®) is a proprietary system of adding a blend of select enzymes to botanical and whole-food products for the purpose of improving the release and absorption of nutrients contained in these products.


This special blend of supplemental enzymes works to extract the nutrients from the formula in the most bioavailable form so your pet's body can use them easily and efficiently.


The L.E.A.D.S.® Live Enzyme Activated Delivery System® is formulated to match the specific needs of each individual product made by NWC Naturals Pet Products and are based on a unique and proprietary method. It is especially beneficial with products providing a whole-food source of vitamins, minerals and pro-biotics.


These tablets do not contain any, chemicals, gluten, soy, dairy, wheat, eggs, preservatives, no artificial coloring or flavoring which may cause reactions in some animals.

Suggested Usage:


One tablet of Total-Zymes® PLUS will treat one cup of any pet food and can be given before or after the meal as a treat.


Tablets may be easily broken in half to treat a 1/2 cup of food per feeding.

Total-Zymes Plus Supplement Facts

1. Is Total-Zymes® PLUS  just for sick pets?


No. This is the most powerful high colony forming formula in the world supplying one Billion CFUs of 14 different strains of good guy bacteria matched to each cup of food consumed. Of course pets that are convalescing definitely will benefit greatly from this product. Total-Zymes® PLUS is designed for daily use for all pets in every cup of food. It is essential that all pets have a daily supplement of probiotics and enzymes to build their susceptible immune systems.


2. What type of research is behind the Total-Zymes® PLUS  formula?

Total-Zymes® PLUS combines the latest research and clinical studies into one powerful formula. The probiotics in this formula were selected after consulting with Dr. Khem Shahani from the University of Nebraska. Dr. Shahani is recognized as one of the world’s foremost authorities on beneficial bacteria supplementation and is a pioneer in the discovery of DDS-1 Acidophilus. In addition, the enzymes have over 30 years of research behind them.


3. Does Total-Zymes® PLUS  have a bad taste?


Total-Zymes® PLUS basically has a subtle carob and brewer’s yeast flavor.  Most pets will just eat it down with their meal. Since it is all human grade ingredients, try it yourself.


4. Can probiotics and enzymes help with constipation in dogs and cats?


Total-Zymes® PLUS for pets can help support a good bowel movement. Probiotics are responsible for controlling the moisture content of the stools. The supplementation of probiotics will help things move along, not by causing a laxative effect but by supporting the natural balance of the colon. Digestive enzymes will help digest the food in the stomach which helps move things along as well.


5. What are enzymes?

Enzymes are products that either begin or enhance the speed of chemical reactions. Present in the cells of plants and animals, they regulate biochemical reactions in both active and inactive forms. They are specific with respect to their functions and do only that which they were designed to do. They have been called the spark of life!


6. Why use non-animal produced or vegetarian enzymes over animal/pancreatic enzymes? 

Vegetarian enzymes are more pure, very proactive, and react faster within their specific task. Animal/pancreatic enzymes, although designed to react the same way, may cause several negative side effects. This is because they may bring inherently non-compatible elements from their originations to your pet. These products generally carry a warning label regarding possible side effects from their use. Pancreatin can also be very aggressive.


7. Why Total-Zymes® PLUS?



The marketplace is full of products that claim to aid in issues of every kind. Many products contain some of the ingredients that help with those issues, yet they do not contain enough of those ingredients to be truly therapeutic.  They may do something to help the issue, but they may not do enough. Other products may use some high quality ingredients, but may compromise elsewhere. At NWC Naturals Pet Products LLC., we use every element necessary to digest any food your pet may consume. We also made sure we added more than enough enzymes and probiotics to do the task completely. When enzymes do their work they must have a supply of high quality chelated minerals to activate the enzymes. These minerals are burned up in that catalytic enzyme activity. If those necessary minerals are not in the digestive enzymes formula itself, then those enzymes will rob the tissues and organs of those minerals in order to accomplish the complete digestion. To prevent this from happening and to enhance the speed and efficiency of our enzyme formula we have added our L.E.A.D.S.® system of patented chelated minerals so the process would be complete unto itself. The L.E.A.D.S.® system is exclusive to NWC Naturals® Pet Products. In addition we have selected the best primary source ingredients so as to enhance our products performance. Total-Zymes® PLUS is the only product with 16 vegetarian enzymes for the total digestive solution and 14 Pro-Biotics with Pre-Biotics.

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